TRPtracker Publication

TRPtracker: a community database for monitoring praziquantel sensitivity at TRPMPZQ variants.

Rohr CM, Park SK, Aguiar-Martins K, Anderson TJC, Berger DJ, Berriman M, Buddenborg SK, Bustinduy AL, Chevalier FD, Cotton JA, Crellen T, Doyle SR, Emery AM, Kincaid Smith J, Kinung'hi S, Lamberton PHL, Le Clec'h W, Ndombi E, Pennance T, Rowel C, Summers SS, Tushabe JV, Walker M, Webster BL, Webster JP, Wilson S, Marchant JS. (2026). Int J Parasitol Drugs Drug Resist. 30:100639. https://doi.org/10.1016/j.ijpddr.2026.100639.

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Published Data Sources

Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni

Berger DJ, Park SK, Crellen T, Vianney TJ, Kabatereine NB, Cotton JA, Sanya R, Elliott A, Tukahebwa EM, Adriko M, Standley CJ, Gouvras A, Kinung'hi S, Rabone M, Emery A, Lamberton PHL, Webster BL, Allan F, Buddenborg S, Berriman M, Marchant JS, Doyle SR, Webster JP. (2026). Science Advances. 12(29):eadt3721. https://doi.org/10.1126/sciadv.adt3721.

Epidemiology and genetic analysis of praziquantel treatment response of Schistosoma mansoni in preschool-aged children in Uganda.

Summers, S. (2025) . PhD thesis, London School of Hygiene & Tropical Medicine. https://doi.org/10.17037/PUBS.04675885

Mechanism of praziquantel action at a parasitic flatworm ion channel

Park, S. K., Friedrich, L., Yahya, N. A., Rohr, C. M., Chulkov, E. G., Maillard, D., Rippmann, F., Spangenberg, T., & Marchant, J. S. (2021). Science translational medicine, 13(625), eabj5832. https://doi.org/10.1126/scitranslmed.abj5832